Investigation of yeast and Drosophila ARF proteins and their associated GEFs expressed in Saccharomyces cerevisiae

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https://osnadocs.ub.uni-osnabrueck.de/handle/urn:nbn:de:gbv:700-201101177664
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dc.contributor.advisorProf. Dr. Jürgen J. Heinisch
dc.creatorBuchwald, Ulf
dc.date.accessioned2011-01-17T13:01:35Z
dc.date.available2011-01-17T13:01:35Z
dc.date.issued2011-01-17T13:01:35Z
dc.identifier.urihttps://osnadocs.ub.uni-osnabrueck.de/handle/urn:nbn:de:gbv:700-201101177664-
dc.description.abstractThe ADP-ribosylation factor (ARF) family of small G-proteins regulates membrane dynamics and intracellular membrane traffic. ARFs are activated upon GTP-binding catalyzed by guanine-nucleotide exchange factors (GEF), which works as a molecular switch and triggers association with specific target membranes. This work focused on the cloning, expression and characterization of genes from the milk yeast K. lactis and the fly D. melanogaster, which are putative homologs of the S. cerevisiae genes GEA1, GEA2, ARF1, ARF2, and ARF3.eng
dc.subjectYeasteng
dc.subjectDrosophilaeng
dc.subjectARFeng
dc.subjectGEFeng
dc.subjectProteinseng
dc.subject.ddc500 - Naturwissenschaften
dc.subject.ddc570 - Biowissenschaften; Biologie
dc.titleInvestigation of yeast and Drosophila ARF proteins and their associated GEFs expressed in Saccharomyces cerevisiaeeng
dc.typeDissertation oder Habilitation [doctoralThesis]-
thesis.locationOsnabrück-
thesis.institutionUniversität-
thesis.typeDissertation [thesis.doctoral]-
thesis.date2010-12-07-
dc.contributor.refereeProf. Dr. Achim Paululat
dc.subject.bk42.13 - Molekularbiologie
dc.subject.bk30.03 - Methoden und Techniken in den Naturwissenschaften
dc.subject.bk30.30 - Naturwissenschaften in Beziehung zu anderen Fachgebieten
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